Endocrine Abstracts

Introduction: Calcium intake is important to prevent osteoporosis in postmenopausal women. The objectives of our study were to evaluate the daily dietary calcium intake in postmenopausal Tunisian women, to compare diabetic and non-diabetic postmenopausal women in their calcium intake and finally to propose corrective interventions to promote calcium intake and minimize the complications of menopause.Subjects and methods: The study involved 73 postmenopau...

Introduction: Dopamine agonist resistance is rare in prolactinoma (10%). Doses of cabergoline of up to 2.0 mg/week are usually effective in controlling prolactin (PRL) secretion and reducing tumor size. Surgical treatment is rarely indicated.Case report: An 18-year-old female presented in 2002 with a 2-year history of amenorrhea and galactorrhea. Hormonal investigation showed a hyperprolactinemia (4800 mUI/l) with integrity of the other pituitary axis. T...

Introduction: Weight loss is a mainstay in the treatment of polycystic ovary syndrome (PCOS). While the cause of this complex endocrine disorder remains unknown, it’s approved that weight loss improves symptoms of PCOS. We report a case of a patient with PCOS. Her symptoms disappeared totally after losing 50kgCase report: In 2005, a 16-year-old girl presented for evaluation of spaniomenorrhoea and obesity. Physical examination showed a weight of 88 ...

Cushing disease (CD) is a rare affection due to an ACTH secreting pituitary adenoma with a hypercorticism as main consequence.The aim of this study was to assess glucose tolerance anomalies in CD.Patients: Twenty-one patients with a diagnosed CD were included; The majority of them (77.3%; n=17) were female. Mean age was 34.2 (19–54 years) and mean BMI 31.9 kg/m2 (25.9–43.7). Mean progression period of ...

Achieving glycemic targets is crucial in the management of diabetes mellitus. Insulin is the most effective hypoglycemic treatment for diabetes but its use can be associated with a risk of hypoglycemia.The aim of this study is to specify risk factors of hypoglycemia in insulin-treated patients.Patients and methods: This transversal study included 69 patients. They were females in 49.4% of cases (n=41). Mean age was 52 year...

Introduction: Type 1 diabetic women have generally more menstrual disorders than healthy women.Objectives: Identify the main mechanisms responsible of menstrual disorders in type1 diabetic women.Patients and methods: We conducted a comparative transversal study including 70 patients with type 1 diabetes: Thirty-three having menstrual disorders (group M) and 37 with regular menses (control group T).We compared...

Objective: The objective of this study was to examine the factors influencing the severity of hepatic steatosis in type 2 diabetes.Methods: Computed tomography imaging was used to assess hepatic fat content in 80 men and women with type 2 diabetes. Inclusion criteria included a confirmed diagnosis of type 2 diabetes (≥1 year of duration), without history of hepatic disease or daily consumption of alcohol drink. The ratio of liver to spleen attenuat...